Adverse Drug Reaction Discovery Using a Tumor-Biomarker Knowledge Graph

نویسندگان
چکیده

برای دانلود باید عضویت طلایی داشته باشید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Statistical methods for knowledge discovery in adverse drug reaction surveillance Statistical methods for knowledge discovery in adverse drug reaction surveillance

Collections of individual case safety reports are the main resource for early discovery of unknown adverse reactions to drugs once they have been introduced to the general public. The data sets involved are complex and based on voluntary submission of reports, but contain pieces of very important information. The aim of this thesis is to propose computationally feasible statistical methods for ...

متن کامل

Improving drug safety: From adverse drug reaction knowledge discovery to clinical implementation.

Adverse drug reactions (ADRs) are a major public health concern, causing over 100,000 fatalities in the United States every year with an annual cost of $136 billion. Early detection and accurate prediction of ADRs is thus vital for drug development and patient safety. Multiple scientific disciplines, namely pharmacology, pharmacovigilance, and pharmacoinformatics, have been addressing the ADR p...

متن کامل

Causality driven data integration for adverse drug reaction discovery

S : scientific #bd14 | big data conference 44 Dr Chen Wang Senior Research Scientist CSIRO Computational Informatics Dr Chen Wang is a Senior Research Scientist at CSIRO Computational Informatics. He received his PhD from Nanjing University. His research interests are primarily in distributed, parallel and trustworthy systems. His current work focus on data analytics systems for drug adverse re...

متن کامل

Recognizing Mentions of Adverse Drug Reaction in Social Media Using Knowledge-Infused Recurrent Models

Recognizing mentions of Adverse Drug Reactions (ADR) in social media is challenging: ADR mentions are contextdependent and include long, varied and unconventional descriptions as compared to more formal medical symptom terminology. We use the CADEC corpus to train a recurrent neural network (RNN) transducer, integrated with knowledge graph embeddings of DBpedia, and show the resulting model to ...

متن کامل

An unusual adverse drug reaction?

INTRODUCTION Adult Still Disease (ASD) is a rare (incidence 1-1,6/1,000,000 in Europe) seronegative polyarthropathy diagnosed with clinical criteria, excluding other etiologies. Minocycline, a semisynthetic derivative of tetracycline, has been associated with many adverse effects. We present the case of a 18-years-old man with a high suspicion of an adverse drug reaction (ADR), that was finally...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

ژورنال

عنوان ژورنال: Frontiers in Genetics

سال: 2021

ISSN: 1664-8021

DOI: 10.3389/fgene.2020.625659